By Ask the Bests Health Editorial Team
What Is VIZZ?
VIZZ (aceclidine 1.44%) is a newly FDA-approved prescription eye drop designed to reduce age-related near-vision blur, known as presbyopia. While Vuity (pilocarpine 1.25%) and Qlosi (pilocarpine 0.4%) arrived earlier, VIZZ stands out by using aceclidine, offering potentially longer-lasting clarity with fewer side effects.
Real-World Performance
- How it works: VIZZ is a miotic agent—it temporarily contracts your pupil to create a “pin-hole effect” that boosts depth of field.
- Speed and duration:
- Onset: ~30 minutes (Vuity acts faster at ~15 minutes)
- Duration: Up to 10 hours, noticeably longer than both Vuity and Qlosi
- Usage form: It comes in single-use refrigerated vials. While less convenient than multidose bottles, the format supports sterility and precision.
Safety & Side Effects
- Dimmed vision in low light: Expect temporary reduced night vision—avoid driving until you assess how you respond.
- Mandatory retinal exam: Required before use to check for rare but serious risks like retinal detachment.
- Minor side effects: Some users may experience redness, mild irritation, or headaches.
Comparisons at a Glance
| Feature | VIZZ | Vuity | Qlosi |
|---|---|---|---|
| Active Ingredient | Aceclidine 1.44% | Pilocarpine 1.25% | Pilocarpine 0.4% |
| Onset / Duration | ~30 min / up to 10 hrs | ~15 min / 6–9 hrs | Varies / up to ~8 hrs |
| Packaging | Refrigerated vials | Room-temp bottle | Refrigerated vials |
| Convenience | Moderate | High | Moderate |
Verdict: Great Potential, but Know What You’re Signing Up For
Advantages:
- Long-lasting clarity—ideal for long workdays or extended near-focus tasks.
- Focused ingredient profile may reduce irritation compared to earlier drops.
Considerations:
- Refrigeration and single-use format may not fit into every lifestyle.
- Initial cost and medical follow-up may outweigh small-scale convenience gains.
Bottom Line: If you’re frequently working up close—whether reading, crafting, or managing devices—and prefer to go without glasses, VIZZ may be a worthy option. But if your reading needs are sporadic, traditional reading glasses remain a low-cost, hassle-free go-to.
