By Ask the Bests Health Editorial Team

What Is VIZZ?

VIZZ (aceclidine 1.44%) is a newly FDA-approved prescription eye drop designed to reduce age-related near-vision blur, known as presbyopia. While Vuity (pilocarpine 1.25%) and Qlosi (pilocarpine 0.4%) arrived earlier, VIZZ stands out by using aceclidine, offering potentially longer-lasting clarity with fewer side effects.


Real-World Performance

  • How it works: VIZZ is a miotic agent—it temporarily contracts your pupil to create a “pin-hole effect” that boosts depth of field.
  • Speed and duration:
    • Onset: ~30 minutes (Vuity acts faster at ~15 minutes)
    • Duration: Up to 10 hours, noticeably longer than both Vuity and Qlosi
  • Usage form: It comes in single-use refrigerated vials. While less convenient than multidose bottles, the format supports sterility and precision.

Safety & Side Effects

  • Dimmed vision in low light: Expect temporary reduced night vision—avoid driving until you assess how you respond.
  • Mandatory retinal exam: Required before use to check for rare but serious risks like retinal detachment.
  • Minor side effects: Some users may experience redness, mild irritation, or headaches.

Comparisons at a Glance

FeatureVIZZVuityQlosi
Active IngredientAceclidine 1.44%Pilocarpine 1.25%Pilocarpine 0.4%
Onset / Duration~30 min / up to 10 hrs~15 min / 6–9 hrsVaries / up to ~8 hrs
PackagingRefrigerated vialsRoom-temp bottleRefrigerated vials
ConvenienceModerateHighModerate

Verdict: Great Potential, but Know What You’re Signing Up For

Advantages:

  • Long-lasting clarity—ideal for long workdays or extended near-focus tasks.
  • Focused ingredient profile may reduce irritation compared to earlier drops.

Considerations:

  • Refrigeration and single-use format may not fit into every lifestyle.
  • Initial cost and medical follow-up may outweigh small-scale convenience gains.

Bottom Line: If you’re frequently working up close—whether reading, crafting, or managing devices—and prefer to go without glasses, VIZZ may be a worthy option. But if your reading needs are sporadic, traditional reading glasses remain a low-cost, hassle-free go-to.

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